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This research theme will focus on characterizing the fast dynamic metabolic changes occurring in tomato (Solanum lycopersicum L.) plant cells/tissue exposed to rapidly changing conditions. This information is crucial to developing metabolic pathway models for the central metabolism of the tomato plant cell. Steady state approaches can be used to quantify fluxes through metabolic pathways. However, to identify the actual regulation and control loops behind these pathways, data from dynamic experiments are required.

Tasks in this research theme are: (i) experiment design, (ii) developing technical requirements like rapid sampling techniques, (iii) performing experiments to measure the response to step changes in various conditions (gas composition, type and concentration of substrates), (iv) performing experiments to measure the response to dynamic changes in various conditions (gas composition, type and concentration of substrates-.

The title of the second project is ‘Dynamics in the central metabolism of Streptomyces lividans producing heterologous proteins’.

If you interest please apply via this site : www.set.kuleuven.be/phd